Active substance: mercaptopurine (mercaptopurine). Pharmachologic effect: Purinethol has antitumor and immunosuppressive effects. It is a very competitive antagonist of purine bases. Indications for usage: acute lymphoblastic leukemia; acute myeloid leukemia; persistent myeloid leukemia (induction of remission and maintenance therapy). Purinethol can be utilized both as monotherapy and in conjunction with other cytostatic in numerous doses, based on the therapy strategy. Normally for adults and children, the dose is 50-75 mg / m2 or 2.5 mg / kg / day; Later, each day Purinethol dosage is altered dependant upon the effect. At first symptoms of serious leukopenia, it is recommended interrupt the take in for 2-3 days. If leukopenia does not intensify during this time period of time, the treatment is started again. In aged sufferers, it is recommended to keep tabs on hardworking liver and renal system function. If symptoms of renal or hepatic failing are detected, the dose should be decreased. The the dose should also be decreased for patients with hepatic and / or renal deficiency.When coupled with allopurinol, the dosage of Mercaptopurine is reduced to 25% of the typical dosage, since allopurinol cuts down on metabolic rate of Mercaptopurine. Get Acheter Purinethol sans ordonnance without prescription on line at the best price.

Side effects. From the side of hematopoiesis: often - leukopenia, thrombocytopenia, anemia. Reactions from the body's defence mechanism: sensitivity reactions: hardly ever - arthralgia, skin rash, drug fever; very rarely - inflammation. On the digestive system part: often - nausea, vomiting, anorexia, intrahepatic cholestasis, hepatotoxicity (hepatotoxicity has a toxic-allergic genesis and occurs when the encouraged dosage of 2.5 mg / kg / day or 75 mg / m2 / day is surpassed; rarely - ulceration of the oral mucosa, diarrhea, pancreatitis, hepatonecrosis; hardly ever - ulceration of the intestinal mucosa. Other: lowered immunity, accession of secondary infections, skin hyperpigmentation; hyperuricemia and nephropathy due to tumor lysis; rarely - the introduction of secondary leukemia, myelodysplasia and hepatolienal T-cell lymphoma. Go through the web page link for More info on Purinethol France and very best location to get Purinethol for cheap.
Contraindications for use are the following: pregnancy; lactation period, allergic reaction to Mercaptopurine or other components in the drug.
Over dose symptoms: instant - feeling sick, nausea or vomiting, anorexia, diarrhea; postponed - myelosuppression, hard working liver dysfunction, gastroenteritis. Special recommendations! Purinethol needs to be used only under doctor’s guidance and the medical doctor should have experience with the utilization of cytostatics. Treatment should be carried out under health-related direction. Do not hesitate to follow the web page link for more info about Mercaptopurine France and best internet site to buy acheter Mercaptopurine pas cher Without Medical prescription for reasonable.